Significance of Acetate Pathway

The acetate pathway in plants is significant for several reasons

  • Production of Phytoconstituents: The acetate pathway is important in the formation of various important phytoconstituents like fatty acids, polyketides, prostaglandins, aflatoxin, tetracycline, and other various important phytoconstituents.


  • Flavonoid and Lipid Biosynthesis: The acetate pathway supports flavonoid and lipid biosynthesis in plants. Flavonoids are secondary metabolites involved in several physiological responses to the environment, such as defense against herbivores, UV radiation, and pathogens. Lipids are essential components of all cells, providing energy storage, insulation, and serving as structural components of cell membranes.


  • Metabolic Sensor: Acetate acts, in part, as a metabolic sensor linking nutrient balance and cellular stress responses with gene transcription and the regulation of protein function.


  • Fatty Acid Synthesis: The acetate pathway operates with the involvement of acyl carrier protein (ACP) to yield fatty acyl thioesters of ACP. These acyl thioesters form the important intermediates in fatty acid synthesis.


  • Production of Secondary Metabolites: The acetate pathway is an important pathway for the production of various secondary metabolites such as straight-chain and aromatic compounds

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